Key Starting Material & Intermediates

1

Benserazide Hydrochloride

2,3,4-Trihydroxy benzaldehyde

[2144-08-3]

2

Benserazide Hydrochloride

DL-Serine hydrazide hydrochloride

[55819-71-1]

3

Irbesartan

2-cyano-4-bromo methyl biphenyl (CBMB) (Irbesartan intermediate)

[114772-54-2]

4

Penciclovir

6-chloro-9h-purin-2-amine (penciclovir intermediate)

[10310-21-1]

5

Solifenacin Succinate

1-Phenyl-3,4-dihydroisoquinoline

[52250-50-7]

6

Solifenacin Succinate

(S)-1-phenyl-1,2,3,4-tetrahydroisoquinoline

118864-75-8

7

Mirtazapine

1-(3-cyanopyridyl-2)-2-phenyl-4-methylpiperazine

[61337-88-0]

8

Mirtazapine

1-(3-carboxy pyridyl-2)-2-phenyl-4-methylpiperazine

[61338-13-4]

9

Mirtazapine

1-(3-hydroxymethylpyridyl-2)-2-phenyl- methylpiperazine

[61337-89-1]

10

Candesartan

(±)-cyclohexyl-1-chloroethyl carbonate (Cilexetil chloride)

[99464-83-2]

11

Ribavirin

1-(2,3,5-tri-o-acetyl-β-d-ribifuranosyl)-1h-1,2,4- triazole-3- carboxylic acid, methyl ester

[39925-10-5]

12

Risperidone

6-fluoro-3-(4-piperidinyl)-1,2, benzisoxazole hydrochloride

[84163-13-3]

13

Bupropion HCL

3-Chloropropiophenone

[34841-35-5]

14

Carvedilol

4-Hydroxycarbazole

[52602-39-8]

15

Pioglitazone

2-(5-ethylpyridine-2yl)ethyl methyl sulfonate

[144809-26-7]

16

Pioglitazone

4-(2-(5-ethylpyridine-2yl) ethoxy) benzaldehyde(pioaldehyde)

[114393-97-4]

17

Pioglitazone

5-[4-[2-(5-ethyl-2-pyridyl) ethoxy] benzylidene]-2,4thiazolidinedione

[627502-58-3]

18

Risperidone

3-(2-chloroethyl)-2-methyl-6,7,8,9-tetrahydro-4h-pyrido[1,2-a] pyrimidan-4-one hydrochloride [Risperidone piperidopyrimidinone]

[93076-03-0]

19

Ribavirin

1-(2,3,5-tri-o-acetyl-β-d-ribofuranosyl)-1h-1,2,4- triazole-3-carboxylic acid methyl ester

[39925-10-5]

20

Gemfibrozil

Isobutyl isobutyrate

[97-85-8]

21

Gemfibrozil

Isobutyl side chain

[109232-37-3]

22

Gemfibrozil

Gemfibrozil isobutyl ester

[148105-26-0]

23

Tafamidis and Agro related

3,5-Dichlorobenzoic acid

[51-36-5]

24

Raw material

3,5-Dichloro Benzyl alcohol

[60211-57-6]

25

Raw material

3,5-Dimethoxy Benzyl alcohol Raw material

[705-76-0]

26

Terbutaline sulphate

3,5-benzyloxy Acetophenone

[28924-21-2]

27

Acalabrutinib

2-Butynoic acid (Tetrolic acid)

[590-93-2]

28

Alfuzosin, Prazosin, Terazosin, Zeftinib

2-Chloro-4-amino-6,7-dimethoxyquinazoline

[23680-84-4]

29

Bepotastine

Pyridine-2-Carboxaldehyde

1121-60-4

30

Bupropion hydrochloride

1-Chloropropiophenone

[34841-35-5]

31

Bupropion hydrochloride

1-chloro-2-bromopropiophenone

[34911-51-8]

32

Bupropion hydrochloride

Bupropion base

[34911-552]

33

Bisoprolol Fumarate

2-[4-[[2-(1-methylethoxy) ethoxy] methyl] phenoxy methyl] oxirane [Bisoprolol Epoxide]

[66722-57-4]

34

Bisoprolol Fumarate

(+_)-1-(4[[2-(1-methylethoxy) ethoxy] methyl]phenoxy]-3-[(1-methylethyl) amino]-2-propanol [Bisoprolol base]

[66722-44-9]

35

Amiodarone hydrochloride

2-butyl-3-(4-methoxybenzoyl) benzofuran

[83790-87-8]

36

Amiodarone hydrochloride

2-butyl-3-(4-hydroxybenzoyl) benzofuran

[52490-15-0]

37

Trimebutine

beta-(dimethylamino)-beta-ethylphenethyl alcohol

[39068-94-5]

38

Nitazoxanide

Nitazoxanide (Base)

55981-09-4

39

Nitazoxanide

2-amino-5-Nitro Thiazole

[121-66-4]

40

Pramipexole

2,6-Diamino-4,5,6,7-tetrahydrobenzothiazole

[106092-09-5]

41

Sertraline Hydrochloride

1-Tetralone

[529-34-0]

42

Anagrelide Hydrochloride Monohydrate

Glycine, N-[(2,3-dichloro-6-nitrophenyl)methyl]-, ethyl ester, hydrochloride (1:1)

[70380-50-6]

43

Avatrombopag (under Developed)

4-(4-Chlorothiophen-2-yl)thiazol-2-amine

[ 570407-10-2 ]

44

Avatrombopag (under Developed)

1-Cyclohexylpiperazine

[17766-28-8]

45

Avatrombopag (under Developed)

5,6-Dichloronicotinic acid

[41667-95-2]

46

Avatrombopag (under Developed)

4-Piperidinecarboxylic acid, ethyl ester

[1126-09-6]

47

Glutamine (under Developed)

Glutamic acid 5-methyl ester

[1499-55-4]

48

Glutamine (under Developed)

N-Boc-L-glutamic Acid 5-Methyl Ester

[45214-91]

49

Glutamine (under Developed)

Di-tert-butyl pyrocarbonate

[24424-99-5]

50

Vonoprazan (under Developed)

5-(2-fluoro phenyl)-1-(pyridin-3-yl sulfonyl)-1H-pyrrole-3- carbaldehyde

[881677-11-8]

51

Vonoprazan (under Developed)

5-(2-FLUOROPHENYL)- 1H-PYRROLE-3- CARBALDEHYDE.

[881674-56-2]

52

Vonoprazan (under Developed)

Pyridine-3-Sulfonyl Chloride

[16133-25-8]

53

Vonoprazan (under Developed)

1-[5-(2-fluoro phenyl)-1-(pyridin-3-ylsulfonyl)-1H-pyrrol-3- yl]-N-methyl methanamine (Vonoprazan Base)

54

Stiripentol (under Developed)

1,3-Benzodioxole-5-carboxaldehyde, 3,4- (Methylenedioxy)benzaldehyde, Heliotropin

[ 120-57-0 ]

55

Zolpidem

2-(4-Methylphenyl)-6-methylimidazo[1,2-a]pyridine

[88965-00-8]

56

Safinamide (under Developed)

4-Hydroxybenzaldehyde

[123-08-0]

59

Lurasidone

(1R,2R)-Cyclohexane-1,2-diyldimethanol

65376-05-8

60

Ropinirol

4-(2-Bromoethyl)-3-chloro-1,3-dihydro-2H-indolin-2-one

120427-95-4

61

FURMONERTINIB

2,6-DICHLORO-3-NITROPYRIDINE

[16013-85-7]

62

Bepotastine

2-[(S)-(4-Chlorophenyl)(4-piperidinyloxy)methyl]pyridine (or) (S)-2-[(4-Chlorophenyl)(4-piperidinyloxy)methyl]pyridine

[201594-84-5]

63

Tafamidis Meglumine

3,5-Dichlorobenzoic acid

51-36-5

64

Lifitagrast

3,5-Dichlorobenzonitrile

6575-00-4

65

Lifitagrast

3,5-Dichlorobenzaldehyde

10203-08-4

66

3,5-Dichlorobenzyl alcohol

60211-57-6

67

Terbutaline Sulfate

3,5-benzyloxy Acetophenone

28924-21-2

68

3,5-Dimethoxy Acetophenone

39151-19-4

69

3-Amino Propionitrile

151-18-8

70

Acalabrutinib

2-Butynoic acid (Tetrolic acid)

590-93-2

71

Nirmatrelvir

Burgess Reagent

29684-56-8

72

O-Benzylhydroxylamine Hydrochloride

2687-43-6

73

Agro Related

N-Hydroxy phthalimide

524-38-9

73

N-Hydroxy succinimide

6066-82-6

74

Ketorolac

Phenyl(1H-pyrrol-2-yl)methanone

7697-46-3

75

Ketorolac

Triethyl (5-Benzoyl-1H-Pyrrol-2YL) Methanetricarboxylate

136116-84-2

76

Ketorolac

5-Benzoyl-2,3-dihydro-1H-pyrrolizine-1-carboxylic acid.

74103-06-3

77

Ketorolac

6,6- Dimethyl 5, 7- dioxa Spiro(2,5) octane 4, 8- dione

5617-70-9

78

Dimethyl[2-(2,3-dibromo-5-benzoylpyrrol-1-yl)ethyl]malonate

80965-18-0

79

Pazopanib

2,3-Dimethyl-6-nitro-2H-indazole

444731-73-1

80

Venetoclax/Vemurafenib

5-Bromo-7-Azaindole

183208-35-7

81

Tenapanor

Benzyl mercaptan

100-53-8

82

Avotrobopag

5,6-Dichloronicotinic acid

41667-95-2

83

Avotrobopag

4-(4-Chlorothiophen-2-yl)-1,3-thiazol-2-amine

570407-10-2

84

Avotrobopag

4-(4-Chlorothiophen-2-yl)-5-(4-cyclohexylpiperazin-1-yl)-1,3-thiazol-2-amine

570407-42-0

85

Avotrobopag

Ethyl 1-(3-chloro-5-{[4-(4-chlorothiophen-2-yl)-5-(4-cyclohexylpiperazin-1-yl)- 1,3-thiazol-2-yl]carbamoyl} yridine-2-yl)piperidine-4-carboxylate

570403-14-4

86

Bedaquiline

3-Benzyl-6-bromo-2-methoxyquinoline

654655-69-3

87

Bedaquiline

3-Dimethylamino-1-(naphthalen-1-yl)propan-1-one hydrochloride

5409-58-5

88

Darolutamide

2-Chloro-4-(1H-pyrazol-5-yl)benzonitrile

1297537-37-1

89

Darolutamide

4-Acetyl-2-chlorobenzonitrile

101667-74-7

90

Darolutamide

4-Bromo-2-chlorobenzonitrile

154607-01-9

91

Vibegron

Tetrahydrofurfuryl chloride

3003-84-7

92

KSM

4,6-Dichloronicotinic acid

73027-79-9

93

KSM

Formamidine Acetate

3473-63-0

94

KSM

4-Bromophthalic anhydride

86-90-8

95

KSM/API

Riociguat

96

KSM

Apixiban

98

G6PD

N-[(3β,5α)-17-Oxoandrostan-3-yl]sulfamide

1373651-41-2

99

Pitrobrutinib

Propanedinitrile, 2-[(4-bromophenyl)methoxymethylene]

1188083-45-5

100

Deferasirox

2- (2-Hydroxyphenyl)-4H-1,3-benzoxazin-4-one

1218-69-5

101

Doxazosin/Alfuzosin

6-Aminoveratric acid

5653-40-7

102

Doxazosin/Alfuzosin

4-Amino-2-chloro-6,7-dimethoxyquinazoline

23680-84-4

103

KSM

Itracanzole Intermediate

104

KSM

2-(tert-butyldisulfanyl)ethanol

86840-29-1